Question

please can you show me the steps of blood clotting

Answer 1

The extrinsic route

Tissue damage releases a substance, tissue thromboplastin, or factor III, which combines with Ca2+ ions and factor VIII, plus tissue phospholipids and enzymes from tissue damage, to activate Factor X,
Factor X is the beginning of the common pathway.

The intrinsic route

Cascade involves factor XII and platelet phospholipids activating Factor XI, which with Ca2+ activates factor IX, factor IX combines with factor VIII, Ca2+ and platelet phospholipids to activate factor X
Endothelial release of factor XII -platelet aggregation - changes in the platelet structure.
Lipids, such as prostacyclins, released from the platelets initiate clotting cascade, -leads to factor X activation, just as in the extrinsic method.

The final common pathway

Factor X, factor V and phospholipids from the cell membranes of damaged tissue and from platelets together form prothrombin activator. The presence of several other factors is necessary, a couple of catalysts (factor IV which is Ca2+ ions, factor V which is a protein catalyst for the activation, and factor VII which is another protein catalyst).
Prothrombin activator, and Ca2+, convert prothrombin to thrombin

Answer 2

http://www.google.co.in/url?sa=t&rct=j&q=&esrc=s&source=web&cd=3&sqi=2&ved=0CFMQFjAC&url=http%3A%2F%2Fwww.manfred.maitz-online.de%2FPublications%2FPresentations%2FBlood-Clotting-Cascade.ppt&ei=Zx-ZUbbSEcumrQfV_oH4Dg&usg=AFQjCNFFO66VIV0AgSpU9h84TeB-G5_Plw&sig2=0NgExxbAX0XttM2hVLSgDg&bvm=bv.46751780,d.bmk

Answer 3

Above is the detailed material for the question above.

Answer 4

1-vascular injury 2-platelets@thromoplastin respond 3-cascade (see above) 4-clot stabilized(F13) 5-fibrinolysis(clot dissolved)-tissue repaired