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Biology 18 Online
OpenStudy (anonymous):

Genetics.

OpenStudy (shrutipande9):

yes..

OpenStudy (anonymous):

A woman with A blood group marries a man with B blood group. Both have their mother with homozygous recessive blood groups. What will be the expected blood groups and the genotypes of their children? Show by making genetic cross.

OpenStudy (shrutipande9):

ok...so do u know which is d homo recessive blood grup?

OpenStudy (anonymous):

No, I think :I

OpenStudy (shrutipande9):

ok...so here the recessive allele is O. So O blood grup is recessive.

OpenStudy (anonymous):

Hmm... Can I ask why is it recessive? O blood group

OpenStudy (shrutipande9):

now both mother and father have 1 parent having blood grup O. so the genotype of that 1 parent is \[I^{O}I^{O}\]

OpenStudy (shrutipande9):

u cannot decide that i want dis allele as recessive so it is recessive...when a particular allele is present against this O allele then O is not expressed. this has been observed so it can be termed as recessive

OpenStudy (shrutipande9):

u getting it?

OpenStudy (anonymous):

I don't know what that i represent :c

OpenStudy (anonymous):

We use that as blood groups genotypes?

OpenStudy (shrutipande9):

yes...like for sex linked genes u write \[X^{n}\]

OpenStudy (shrutipande9):

its \[I^{A/B/O}\] HERE

OpenStudy (anonymous):

So for blood groups we use i instead of x ? Got it! Okay, only O blood group is recessive? :I

OpenStudy (shrutipande9):

yes...this is an eg of multiple alleles. earlier u studied dat der are 2 alleles 1 recessive and 1 dominant...but sometimes u hv more than 2 alleles. here a is dominant over o b is dominant over o but a is incompletely dominant over b. so v get ab blood group.

OpenStudy (shrutipande9):

so now as i told u earlier each 1 of the parent has IOIO blood grup

OpenStudy (anonymous):

Now I have to cross them?

OpenStudy (shrutipande9):

not so early...now mother and father's parent has that genotype. so out of these one would be giveen to the child. so one of the allele of mother and father is \[I^{O}\]

OpenStudy (shrutipande9):

Now mother's blood group is given as A so u the other allele must be \[I^{A}\] And fathers is given as B so the other allele has to be\[I^{B}\]

OpenStudy (shrutipande9):

So the genotype of mother is iaio and thaat of father is ibio. remeber i told u...A is dominant over O and B is dominant over O

OpenStudy (anonymous):

Oh no, I'm confused.

OpenStudy (shrutipande9):

confused where?

OpenStudy (shrutipande9):

wait ill try 2 draw a diag for u

OpenStudy (anonymous):

Why A is dominant over O? And B is dominant over O?

OpenStudy (shrutipande9):

Because that is what has been observed.

OpenStudy (anonymous):

Okay. It always remain the same? I mean, A dominant over O and B dominant over O? Or only in this problem..?

OpenStudy (shrutipande9):

always...in case of blood groups.

OpenStudy (anonymous):

Alright!

OpenStudy (shrutipande9):

so u got how v get d genotype of mother and father?

OpenStudy (shrutipande9):

mother-\[I ^{A}I ^{O}\]

OpenStudy (anonymous):

IOIA mother's ? IOIB father's ?

OpenStudy (shrutipande9):

YES CORRECT

OpenStudy (shrutipande9):

But while writing generally the dominant allele is written first. now u cross these genotypes.

OpenStudy (shrutipande9):

so wat do u think would be the possible genotypes of children after a normal cross?

OpenStudy (anonymous):

IAIB IAIO IBIB IBIO

OpenStudy (anonymous):

I did it right? :I

OpenStudy (shrutipande9):

genotype-IAIO X IBIO gametes-IA IO IB IO children- IAIB IAIO IBIO IOIO

OpenStudy (shrutipande9):

yes..but in place of IBIB it should be IOIO

OpenStudy (shrutipande9):

so now IAIB would be AB IAIO-A IBIO-B IOIO-O

OpenStudy (shrutipande9):

GOT IT?

OpenStudy (anonymous):

I crossed it wrong with B instead of O

OpenStudy (shrutipande9):

YES...rest everything was perfect:)

OpenStudy (shrutipande9):

u got it dude:)

OpenStudy (anonymous):

So, IAIB means AB bloodgroup? IBIO means B bloodgroup? IOIO means O bloodgroup?

OpenStudy (shrutipande9):

yes..because b is dominant over o so u get b a dominant over o so u get a and a and b are incompletely dominant so u get both ab.

OpenStudy (anonymous):

I got it now. Now I have to find children genotype?

OpenStudy (shrutipande9):

see basically des blood grups depend on the antigen u have...B blood grup has antigen B A has antigen A O has no antigen and AB has both antigen A and B.

OpenStudy (shrutipande9):

U just did...by crossing the parents..rite?

OpenStudy (shrutipande9):

i g2g now ryaan...hope ur doubts are cleared?

OpenStudy (anonymous):

Oh right..lol Question is asking to find possible bloodgroups and genotypes of children, so I got confuse. I thought now I have to find genotypes. Thank you for explaining me! :-)

OpenStudy (shrutipande9):

nope...u got it all rite dude...bye for now...tag me if u hv ne genetics problems:)

OpenStudy (shrutipande9):

happy 2 help:)

OpenStudy (anonymous):

Sure I'll ask you, I still have some confusion with these genetics problems! Thanks again:)

OpenStudy (shrutipande9):

someday when v hv time...v will start from d basics of genetics:)

OpenStudy (anonymous):

I have some confusion can I ask?

OpenStudy (shrutipande9):

yes...go ahead

OpenStudy (anonymous):

If parents blood groups are given to me as A both Mom and dad's. But not their mother's blood groups are given.. How do I find their genotypes and how do I cross them too see what will be their children bloodgroup and genotypes?

OpenStudy (shrutipande9):

what would be the possible genotypes of mom and dad? wat do u think?

OpenStudy (shrutipande9):

in earlier prob it was given 1 parent has O so 1 allele has 2 be IO. but in this thats not true. rite?

OpenStudy (anonymous):

For blood group A, you told me A has antigen A only. So that would be AA?

OpenStudy (shrutipande9):

yes...and?

OpenStudy (anonymous):

So, for father..It'll be AA too? Now how do I cross them? when I don't know what their other alleles are. In that previous problem Mother and father's mother were given O.. But now I have another problem but parents mothers bloodgroup are not given... So how do I make a cross?

OpenStudy (shrutipande9):

ok wait...lets forget about this problem for now...

OpenStudy (shrutipande9):

lets suppose i have a dominant allele A and a recessive allele O. A gives me red colour and O gives me white colour ok? what possible genotype combinations can u get from these 2 alleles?

OpenStudy (shrutipande9):

it can be homo or hetero...give me all the possible combinations.

OpenStudy (anonymous):

*Confused* :I

OpenStudy (shrutipande9):

ok lets start from the start then...u know that every gene has 2 alleles?

OpenStudy (shrutipande9):

*in normal cases

OpenStudy (anonymous):

besides blood types?

OpenStudy (shrutipande9):

i m talking about general genes...it can be anything...leave d blood groups aside for a while because bood groups are an exception. we will talk about the general statements first.

OpenStudy (anonymous):

Okay!

OpenStudy (anonymous):

Every gene has 2 alleles.

OpenStudy (shrutipande9):

good..so out of these 1 is dominant and 1 is recessive.

OpenStudy (anonymous):

2 alleles can't be dominant?

OpenStudy (anonymous):

Means both?

OpenStudy (shrutipande9):

so when we consider a genotype u can get 2 dominants together 2 recessive together or 1 dominant 1 recessive together.

OpenStudy (shrutipande9):

its like a jigsaw puzzle...u hv only 2 places that are need 2 b filled and i give u a whole set of dominant and recessive alleles. at a time u can use only 2.

OpenStudy (shrutipande9):

so lets consider A is dominant and a is recessive. it is generally abbreviated in this manner...dominant capital recessive small

OpenStudy (shrutipande9):

now can u tell me d possible combinations?

OpenStudy (anonymous):

Aa you mean?

OpenStudy (shrutipande9):

yes...and what else? u can also have 2 dominant together and 2 recessive togder rite?

OpenStudy (anonymous):

Right right!

OpenStudy (shrutipande9):

so now tell me all d combinations.

OpenStudy (anonymous):

AA, aa, Aa

OpenStudy (shrutipande9):

exactly....:) now AA and aa are called homozygous because they have same allele in a pair while Aa is called heterozygous...ook?

OpenStudy (anonymous):

Okaaaaay! :3

OpenStudy (shrutipande9):

good...can i go ahead?

OpenStudy (shrutipande9):

let us consider that A gives me red flowers and a gives me white flowers. so when u have AA obviously u r going 2 get red flowers and in aa u get white flowers...ok?

OpenStudy (anonymous):

Right.

OpenStudy (anonymous):

I have a question.

OpenStudy (shrutipande9):

ok...wat?

OpenStudy (anonymous):

Alleles are when we make a pair? means AA they both are called alleles?

OpenStudy (shrutipande9):

alleles when in a pair make a genotype....in a diploid person 2 alleles required.

OpenStudy (shrutipande9):

u got it?

OpenStudy (anonymous):

Here you said (AA and aa are called homozygous because they have same allele in a pair) How they have same allele in a pair? Here we call them as alleles?

OpenStudy (shrutipande9):

aa has both alleles as a? while in AA both are A?

OpenStudy (shrutipande9):

A- is an allele....AA-is a genotype.

OpenStudy (anonymous):

Means together they are called genotype and if we separate them it will be called an allele?

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