Question

A mutation in the EGFR gene that replaces the tyrosines located on the cytoplasmic domain with phenlyalanines, is it likely to lead uncontrolled division?

Answer 1

Maybe this will help. :P
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092428/

Answer 2

Thanks!

Answer 3

Anytime. :P

Answer 4

see phosphorylation occurs to the tyrosine residues...so if they r replaced then no phosphorylation.

Answer 5

thus prevents the further cascading effect...so the ned result of the effect that is the gene is expressed does not occur...

Answer 6

:Dhope this helped

Answer 7

Thank you!