Huntington's disease causes a slow degeneration of the nervous system, beginning at about age fifty. Patients with Huntington's disease lose control of their limbs and become forgetful. As the disease grows more severe, it paralyzes and kills them. The disorder is dominant.
Suppose that Bill's genotype is (Hh) and his wife Sharon is (hh). What are the chances that his daughter, Grace, will also have Huntington's?

Question

Huntington's disease causes a slow degeneration of the nervous system, beginning at about age fifty. Patients with Huntington's disease lose control of their limbs and become forgetful. As the disease grows more severe, it paralyzes and kills them. The disorder is dominant.
Suppose that Bill's genotype is (Hh) and his wife Sharon is (hh). What are the chances that his daughter, Grace, will also have Huntington's?

saylilbaby · Answer

A)
0%	
B)
25%	
C)
50%	
D)
100%
i think its D.100% @Abhisar and @Directrix

abhisar · Answer

To find out this let's draw a punnet square for cross between Hh and hh

abhisar · Answer

|dw:1419715041978:dw|

abhisar · Answer

So, only the genotypes having H (the dominant one) in them will express Huntington's disease.

anonymous · Answer

This is just probability (mendelian genetics)

abhisar · Answer

Total no of genotypes is 4 and out of it 2 contains H, so what should be the probability?

saylilbaby · Answer

so it would be C 50%

abhisar · Answer

$\huge \checkmark$