OpenStudy (anonymous):
Describe in detail the two molecular processes in steroid and peptide action
OpenStudy (anonymous):
Peptide hormones need a receptor in the cell membrane. The hormone binds to the receptor stimulating a second messenger within the cell which causes a phosphorylation cascade, that eventually reaches the target molecule. http://classconnection.s3.amazonaws.com/80/flashcards/3621080/png/cascade_of_phosphorylation-140C741FEF94B6523AE.png Steroid hormones are non-polar so can pass through the cellular membrane. Inside the cytoplasm (or nucleus) they bind to steroid receptors and are escorted into the nucleolus. The steroid-receptor complex binds to DNA and initiates transcription of mRNA, which is then translated to a protein which effects the cell. http://www.usmle-forums.com/images/added/attachments/inpost/gre.jpg
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