Predict the structure of the conjugate acid of procaine.
• Calculate the Kb and pKb of procaine.
• Discuss which species, procaine or its conjugate acid, is stronger in terms of their acid-base reactivity with water.

Question

Predict the structure of the conjugate acid of procaine.
• Calculate the Kb and pKb of procaine.
• Discuss which species, procaine or its conjugate acid, is stronger in terms of their acid-base reactivity with water.

revircs · Answer

Procaine (C13H20N2O2) is a local anesthetic used primarily to reduce the pain from penicillin injection, and it is also used in dentistry. For basic drugs such as procaine, it is
common to report the value of the pKa of their conjugate acid instead of the pKb of the actual base. The pKa of the conjugate acid of procaine has a value close to 8.

revircs · Answer

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revircs · Answer

I know the the conjugate acid would have an extra proton, I just dont know where it would be placed on the structure.

photon336 · Answer

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