Question

How long can organs live outside the body and what causes them to fail?

Answer 1

I was thinking temp and PH vales might have something to do with it but that's just a guess.

Answer 2

Usually organs are frozen when they want to be transported to some other place so a organ transplant can take place. But I'm guessing probably under 12 hours for most organs like kidneys. For the hear though if I'm not wrong it's a few precious minutes. So when a person is brain dead, heart surgeons have about 12 mins I think to remove the heart and freeze it. And it'll prob be aalright for the next few hours before infections occur yup

Answer 3

the viability of organ varies from several hours to around24h in the case of a kidney.
as in most cases - i would guess that cellular hypoxia will lead to cellular death. w/o oxygen for a long time, no ATP to keep membrane potential and membrane integrity. w/o oxygen anaerobic glycolysis will occur and acidity will increase as well

Answer 4

I second hypoxia leading to failure

Answer 5

So let’s say if hypoxia never happens such as having blood or blood substitute being pumped to and from the organ, would infection be only cause of failure?