Addictive drugs produce changes in one particular group of synapses that use the neurotransmitter _____.
I guess there is no such a particular group; for example; Cocaine (benzoylmethylecgonine) (INN) is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant.[5] The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine. It is a stimulant of the central nervous system, an appetite suppressant, and a topical anesthetic. Specifically, it is a serotonin–norepinephrine–dopamine reuptake inhibitor (also known as a triple reuptake inhibitor (TRI)), which mediates functionality of these neurotransmitters as an exogenous catecholamine transporter ligand. It is addicting because of the way it affects the mesolimbic reward pathway.[6] Affects serotonin, norepinephrine and dopamine! Now, for Nicotine; Nicotine has a higher affinity for acetylcholine receptors in the brain than those in skeletal muscle, though at toxic doses it can induce contractions and respiratory paralysis.[26] Nicotine's selectivity is thought to be due to a particular amino acid difference on these receptor subtypes.[27]] Then, we have two of the most importante addictive drugs and we don´t have only one group. Because acetylcholine is not affected by cocaine. Then, if you check "Morphine" you will find that affects opioid receptors; Opioid receptors are a group of G protein-coupled receptors with opioids as ligands.[1][2][3] The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are ~40% identical to somatostatin receptors (SSTRs). Opiate receptors are distributed widely in the brain, and are found in the spinal cord and digestive tract.
u can simply give the link too @Marrioncito :)
Ok, but there were three links. And I quoted a 1/20 part of each article :P Look for; nicotine, cocaine, morphine..
I must said that is from Wikipedia...but..what else could it be? Encarta? :P haha. THank you
yw :)
They're probably looking for dopamine as the answer.
I say serotonin
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