For a reaction where the formation of product is energetically favored, but the formation of product from reactant requires an enzyme, indicate if each of the following statements is true or false. The product would be at a higher free energy state as compared to the reactant. True False
The reactant would be at a higher free energy state as compared to the product. True False
There is an intermediate molecule at a higher free energy state as compared to the product. True False
There is an intermediate molecule at a higher free energy state as compared to the reactant. True False
The enzyme decreases the difference in free energy (ΔG°‘) between the reactant and the product. True False
The enzyme decreases the difference in free energy (ΔG°‘) between the reactant and the intermediate. True False
Enzymes hold it's substrate (reactant) at a conformation (structure) that is closer to that of the intermediate so it removes some of needed Gibbs free energy for the complex to achieve this intermediate state. But they do not change the free energy difference of the reactant (lacking the enzyme) and the product. Look up entatic state theory if you're interested. (sorry i can't give you straight answers)
watch this video, its short and to the point. http://www.youtube.com/watch?v=Dd1yi2aVoOc
thanks
no problem
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