In which part of the nephron are sodium and chloride ions actively reabsorbed?
What is the role of ADH (antidiuretic hormone) in regulating salt and water concentrations in the blood?
That would be Proximal tubule..
The most important effect of antidiuretic hormone is to conserve body water by reducing the loss of water in urine Antidiuretic hormone stimulates water reabsorbtion by stimulating insertion of water channels or aquaporins into the membranes of kidney tubules. These channels transport solute-free water through tubular cells and back into blood...
thick ascending limb of loop of henle?key word is actively transported ....and chloride in question....na/k/2cl transport is in ascending limb of loop of henle
ADH acts on collecting duct
Sodium Excretion Proximal Tubule 1. Active reabsorption at the interstitial (basolateral) surface 2. Passive cotransport with glucose and amino acids and other organic molecules at the luminal (apical) surface 3. Antiport exchange with H+ ion at the luminal surface 4. Total reabsorption is a constant fraction of the filtered load, about 70%; this is termed glomerular-tubular balance 5. The active reabsorption of Na+ and the accompanying cotransport of other substances creates the osmotic gradient leading to the reabsorption of water 6. Controlled by a. renal sympathetics: increase Na reabsorption b. Angiotensin II: increase Na reabsorption Loop of Henle 1. Descending thin limb: little transport 2. Ascending thin limb: passive reabsorption 3. Ascending thick limb: active reabsorption at the interstitial (basolateral) surface and passive cotransport with K+ and Cl- at the luminal (apical) surface 4. The active reabsorption of Na+ and the accompanying cotransport of other ions is important in establishing the high medullary osmotic activity (increased by countercurrent multiplication) necessary for adjustment of urine tonicity by the collecting duct 5. Controlled by a. renal sympathetics: increase Na+ reabsorption b. Aldosterone: increase Na+ reabsorption Distal Tubule and Collecting Ducts 1. Active reabsorption at the interstitial (basolateral) surface 2. Passive movement into the cell through Na+ channels at the luminal (apical) surface 3. Controlled by a. renal sympathetics: increase Na reabsorption b. Aldosterone: increase Na reabsorption c. Atrial Natriuretic Peptide (ANP): decrease Na reabsorption d. Urodilatin: decrease Na reabsorption
Let me simplify this for everyone.. B. Loop of Henle
Join our real-time social learning platform and learn together with your friends!