Question

***MITOSIS QUES!!!!***
is cohesins replaced by condensins or vice versa during mitosis? also later which protein is degraded by separase enzyme in anaphase?

Answer 1

Im sorry I can't help you here im really confused now.

Answer 2

no problem..:)

Answer 3

I had to google it, because i had a difficult time understanding it lol really sorry

In cells that fully condense their chromosomes at mitosis, as vertebrate cells
do, much of the cohesin is released from the chromosome arms at the start
of mitosis, when chromosome condensation begins. With most of the
cohesin out of the way, the cell can coil individual sister chromatids into
separate domains. The small amount of cohesin that remains is sufficient to
hold sister chromatids together until anaphase, when the residual cohesins
are degraded.
source: google.com

Answer 4

srry...i was thinking of writting the details first and then the ques...
so separase degrades cohesin? and due to this the sister chromatids separate during anaphase?

Answer 5

separase degrades cohesin? I believe so, it degrades after the activation of Proteolysis of securin at the transition of metaphase-to-anaphase.

Answer 6

In other words, Separase is initiated by the degradation of its inhibitor securin

Answer 7

and inhibitory phosphates getting removed

Answer 8

Here's a site, hope it gives all the info that i didn't provide
http://www.wikigenes.org/e/gene/e/9700.html

Answer 9

thank u soo mch zale!!!:D

Answer 10

you're welcome !!

Answer 11

is this the question that needed clarification?

Answer 12

when unsure, always imagine the pathways - negative feedback and positive feedback. those two kind of give you an overview of what is going on. one pathway may involve multiple systems, such as what you were asking.

Answer 13

Now I guess ur ans needs clarification nin...