Question

can anyone explain endochondral ossification?

Answer 1

Endochondral ossification is one of the two processes during fetal development of the mammalian skeletal system in which bone tissue is created. It is also an essential process for the rudimentary formation of long bones,increasing the length of long bones, and healing of bone fractures.Unlike intramembranous ossification, which is the other process, endochondral ossification requires a pre-existing cartilage model.

Answer 2

can you explain the process step by step, because my teacher explained it too fast.

Answer 3

step 1

As cartilage enlarges, chondrocytes near center of shaft (diaphysis) increase in size and surrounding matrix begins to calcify. Deprived of nutrients chondrocytes begin to die
step 2
perichondrium surrounding the cartilage differentiate into osteoblasts. Perichondrium converts to periosteum and the osteogenic layer produces a bony collar around shaft of cartilage.
step 3
capillaries and osteoblasts migrate into the heart of the cartilage, into spaces left by chondrocytes. the calcified matrix breaks down and osteoblasts replace with spongy bone. This becomes Primary Ossification Center in the shaft (diaphysis).
step 5
Centers of the epiphyses now begin to calcify. Capillaries and osteoblasts migrate to these area, creating Secondary Ossification Centers.
step 6
The epiphyses eventually become filled with spongy bone. A thin cap of cartilage remains exposed to join cavity as Articular Cartilage. At metaphysis, the epiphyseal plate separates the epiphysis from the diaphysis.

Answer 4

step 4?

Answer 5

blep sorry I just took it out of my notes!

Answer 6

step 4

The entire diaphysis is filled with spongy bone but as it enlarges, osteoclasts erode the central portion to create Medullary Cavity. Growth involves increase in length and diameter.

Answer 7

thank youu :3

Answer 8

is step 4 supposed to be step 5 and step 5 is step 4?

Answer 9

nope!