Question

BRCA1 mutation

BRCA2 mutation

No BRCA mutation

Total

Number of patients

89

35

318

442

Average age at diagnosis

43.9

46.2

50.4



Preventative mastectomy*

6

3

14

23

Preventative oophorectomy*

38

7

22

67

Number of deaths

16

1

21

38

Percent died

18

2.8

6.9

8.6

Answer 1

Describe how mutations lead to genetic variations.
Which appears to be more dangerous: the BRC1 or BRC2 mutation?
Analyze a woman’s risk of dying of cancer if she carries a mutated BRC1 gene.
How do heredity and inheritance relate to the data presented in these charts?
What data would you need to see in order to draw conclusions about the effectiveness of preventive surgeries?
What does the age at diagnosis tell you about the mutation?
Explain how breast-cancer genes are still present in the population, despite cancer-related surgeries and deaths.

Answer 2

compare the data

Answer 3

for example: "Which appears to be more dangerous: the BRC1 or BRC2 mutation?"

Percent died: 18 (BRCA1), 2.8 (BRCA2)


Clearly the BRCA1 is more dangerous because more people died

Answer 4

or a higher percentage died (not more people)

Answer 5

I know the other ones what do you think about this question? How do heredity and inheritance relate to the data presented in these charts?

Answer 6

hm do you know what inheritance pattern the BRCA1 genes have?

Answer 7

i meant BRCA1 and 2

Answer 8

mmmhmm

Answer 9

you should look into that