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Biology 22 Online
OpenStudy (anonymous):

Could someone help me understand the polarity in double stranded DNA? I don't get if it is polar or not, and if it is why. What does the polarity mean in regards to the bigger picture?

OpenStudy (shrutipande9):

heya nelso! welcome to openstudy!!

OpenStudy (shrutipande9):

dna definitely has polarity....each strand has a 5' and 3' end

OpenStudy (shrutipande9):

this 3' and 5' refers to the carbon of the deoxyribose sugar....

OpenStudy (anonymous):

Yes, but I guess I don't understand where this polarity is coming from and why it creates polarity. & thank you!

OpenStudy (shrutipande9):

other thing is...net charge on DNA is negative...this is mainly because of the phophate group.. see 2 O of the phosphate are bound to 2 deoxyribose...and other 2 remain unbound...so these oxygen ions ie O- create the negative charge

OpenStudy (anonymous):

okay! I think that makes sense. do you know if the polarity of DNA affects anything, like interactions with other parts of the cell?

OpenStudy (shrutipande9):

ohh yes...it definitely affects other parts...basically this negative charge and the hydrogen bonding between the nitrogen bases gives DNA its peculiar double helical structure....plus this negative charge tends to repel a lot of ions and moleculess keeping the DNA stable.....it maybe enhances or reduces the binding of different enzymes and factors used in replication transcription etc... i hope this helps:D

OpenStudy (anonymous):

very much! thank you!! (:

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