Question

HELP!!!
Galactosemia is an autosomal recessive human disorder that affects 1/250,000 individuals in Sweden. Individuals with galactosemia have genotype “gg”. What is the frequency of the recessive allele in this population?
Answer

0.0002


0.02

0.002

0.99
I don't know I got a weird number I did 2/500,000 help!

Answer 1

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Answer 2

please help @Abhisar

Answer 3

LOL..what happened ? r u in a test ?

Answer 4

no I need it done by tonight.

Answer 5

all ryt..give me a minute then

Answer 6

A is the answer

Answer 7

show me the math behind it?

Answer 8

since it is a recessive disease...the genotype of the affected person will be (gg)

Answer 9

Now the frequency of disease i.e of gg is given 1/250,000

Answer 10

u need to calculate frequency of g

Answer 11

it will be \[\sqrt{1/250,000}\]

Answer 12

The answer i gave u is wrong !

Answer 13

what is it???

Answer 14

I cant say that..

Answer 15

........

Answer 16

is it C?

Answer 17

I dont know....i think the question provides insufficient informations !

Answer 18

It does not, trust me.

Answer 19

since it is a reccesive allele we use "2" instead of "1" because 2 alleles contribute to the reseccive like, and divide that by 500,000 because of allele frequency and sqaure root it.....

figured it out.

Answer 20

what about the people who have genotypes Gg..have u included them in ur calculation ?

Answer 21

@alphadxg

Answer 22

Since it is recessive, then it wouldn't matter the disorder is only present when gg appears, since gg has two allels then you use 2/2500 square root that. = .002

Answer 23

ohkay here we have to find the frequency of allele g...what about g in Gg ?

Answer 24

@Abhisar answered it already :)

http://openstudy.com/study#/updates/538aa805e4b02fec90351442

Answer 25

No m asking different hink...u hav to calculate the frequency of allele g in this question..so u will hav to include the g in Gg also

Answer 26

@alphadxg

Answer 27

What is the frequency of the "recessive allele" in this population? It's not asking us for heterozygotes.

Answer 28

yes but recessive allele is g and it is also in Gg

Answer 29

@alphadxg

Answer 30

@alphadxg is right, submitted my test and it was right answer. thanks boys @abhisar