Question

can anyone explain me transcription

Answer 1

@deepika.comet @shereenkhan @Abhisar

Answer 2

lets start with the basic web definition:
Transcription is the process by which the information in a strand of DNA is copied into a new molecule of messenger RNA (mRNA). DNA safely and stably stores genetic material in the nuclei of cells as a reference, or template.

Answer 3

Now lets discuss what parts dont make any sense to you?

Answer 4

just give me a sec @PRAETORIAN.10

Answer 5

take all the time you need gurl :D

Answer 6

thats fine

Answer 7

RVC = Regimental Victorian Civilians

Answer 8

It is the process by which DNA is copied into mRNA with the help of enzymes. Have a look on this link for detailed explanation of the process
` http://biology.about.com/od/cellularprocesses/ss/Dna-Transcription.htm `

Answer 9

i did not understand the web def

Answer 10

https://www.youtube.com/watch?v=WsofH466lqk

Answer 11

thats because Ab the Awful doesnt know what he is talking about ;)

Answer 12

can u explain me the process step wise @PRAETORIAN.10

Answer 13

Binds to the DNA strand at a specific sequence of the gene called a promoter
Unwinds and unlinks the two strands of DNA
Uses one of the DNA strands as a guide or template
Matches new nucleotides with their complements on the DNA strand (G with C, A with U -- remember that RNA has uracil (U) instead of thymine (T))
Binds these new RNA nucleotides together to form a complementary copy of the DNA strand (mRNA)
Stops when it encounters a termination sequence of bases (stop codon)

Answer 14

thats copied and pasted but probs makes more sense then what i would write because according to Ab my terminology is too advanced ;)

Answer 15

does that process make more sense now?

Answer 16

just wait
let me read it

Answer 17

righto bucko

Answer 18

I'm more of a visual person, so that video might help.

Answer 19

agreed, everyone has a unique way of learning, trial and error for some. try and fail and fail and fail for people like Ab. Try one time and get it right every time for me. etc etc

Answer 20

If you know what kind of learner you are then it'll be easier for you to, well....learn.

Answer 21

~ nom nom nom i need to eat something hungry hungry Prae ~

Answer 22

i'll be back unless i find food in which case i wont be back because doctors are fatties and i love cookies

Answer 23

in the event of such, i have tasked squire Ab to assist you in every need

Answer 24

u may leave thx :)

Answer 25

Read Pg 107 and ask me if u get stuck anywhere :)

Answer 26

where is the promoter present?
@Abhisar

Answer 27

On the DNA

Answer 28

Promoter in just the name of a DNA region which promotes transcription

Answer 29

at 5 end right?

Answer 30

yes 5' end of the coding strand

Answer 31

what is monocistronic?

Answer 32

Monocistronic means such a RNA which can code for only one polypeptide per RNA molecule.

Answer 33

Polycistronic means such a RNA which can code for more tha one polypeptide per RNA molecule.

Answer 34

Bacteria and other prokaryotes have polycistronic type of RNA while Eukaryotes have monocistronic type of RNA

Answer 35

can u make it little simple

Answer 36

:O

Answer 37

ok what part u r not able to get in the above lines ?

Answer 38

which can code 4 more than 1 polypeptide chain

Answer 39

Monocistronic RNA --------> A single RNA can code for only one polypeptide, found in eukaryotes

Polycistronic RNA ------> A single RNA can code for more than one polypeptide, found in prokaryotes

Answer 40

means it will code 4 only one polypeptide
the same RNA will not go for other polypeptide chain = monocistronic

Answer 41

am i correct

Answer 42

\(\huge\checkmark\)

Answer 43

THANK U
im glad im understanding

Answer 44

you're most welcome :)

Answer 45

in hnRNA :splicing process does not undergo?

Answer 46

in hnRNA besides splicing an additional process called caping and tailing also takes place.

Answer 47

yes but in splicing introns go right?

Answer 48

so how do they say hnRNA have (introns as well as extrons) in bracket?

Answer 49

In eukaryotes, primary transcript contains both introns and exons. Introns are useless and intervening sequences and make the primary transcript non functional. in order to make the transcript functional these introns are needed to be removed. This is achieved by the process of Splicing. In this process introns are removed and exons are jined in a definite order.

Answer 50

small caveat, introns are not useless.

Answer 51

hnRNA is a type of RNA [one from several other] which is precursor of mRNA. During its transcription an additional process called capping and slicing is required. So in their case splicing is followed by capping and tailing

Answer 52

introns are definitely not "useless".

Answer 53

another caveat, splicing can occur at the same time as capping

Answer 54

Someone needs to go back to Bio 101.

Answer 55

Introns are intervening sequences which do not appear in mature RNA

Answer 56

I used the term useless just to simplify things.

Answer 57

Afterall nothing in the human body is useless :)

Answer 58

cept your appendix

Answer 59

rekt

Answer 60

Everything is bit important yes that we know.

Answer 61

@jedi_trooper if u'll dig a little deeper then u'll find that appendix has its use too.

Answer 62

OOOOOOOOOH!!! U GON TAKE THAT, JEDI!?

Answer 63

@jedi_trooper

Answer 64

But we can totally live without it just like living with one kidney

Answer 65

Just because something's function is unknown or not well understood u can not say that it's useless. Check out some good physiology books and u'll find that they act as a rservoir for prebiotics.

Answer 66

says the guy who calls introns useless

Answer 67

lol

Answer 68

I already clarified why i said it useless !

Answer 69

I used the term useless just to simplify things. it has no role in mature RNA.

Answer 70

also its function is very insignificant !

Answer 71

@abb0t @jedi_trooper
http://en.wikipedia.org/wiki/Intron#Biological_functions_and_evolution

Answer 72

Wikipedia is not that reliable... <->_<-> hmmm

Answer 73

But oh wells some are reliable

Answer 74

But that's correct. You can search it anywhere else too
http://prntscr.com/4ivjqj

Answer 75

lol you called its function insignificant and then linked a wikipedia article that describes very important functions that introns play a role in.

Answer 76

Like ?

Answer 77

it contains sequences necessary for splicing. can generate non-coding RNA which in turn plays many regulatory roles.

Answer 78

I don't see the word "useless" anywhere in that article.

Answer 79

The term useless was with respect to splicing

Answer 80

Introns are only relatively recently being studied in depth, so there is still much to learn about them.

Answer 81

Introns have a huge role in splicing though

Answer 82

And yes i agree it's not a very scientific term !
It was just used to make things simple.

Answer 83

what you trying to prove? What's been said is been said.

Answer 84

i mean has* been said

Answer 85

Well, for the sake of high school Biology, introns are deemed useless cause they're too lazy to go into depth about these concepts.

Answer 86

But, we should hold ourselves to a higher standard!

Answer 87

You're so right, @jedi_trooper thank you for correcting and providing us with proper information.

Answer 88

This is not a competition @jedi_trooper !
The asker is an A level student and i was just making sure she get things

Answer 89

btw thank you for ur kind words @jedi_trooper @abb0t !
:)

Answer 90

But are they going to really use it in their daily lives? If they're planning to have a career in this area then yeah it is..

Answer 91

I know. I meant my comment to be a small footnote in your lecture, but you got sidetracked. lol

Answer 92

Though awesome information learning that. lol haha :)