Question

Suppose you took a drug that increased the permeability of the inner mitochondrial membrane, allowing some dissipation of the H+ gradient established by the electron transport system. What effects would that have on your body temperature, efficiency of energy utilization, and health? As always, I want you to write a comprehensive and thoughtful essay.

Answer 1

WELL WHAT IS THE ROLE OF IONS INSIDE AND OUTSIDE OF MITOCHONDRIA?

Answer 2

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712118/

Answer 3

@jabez177 @RamiroCruzo

Answer 4

toxic u have to write this urself im sorry theres just no way of giving it to u

Answer 5

i really wished i could help trust me im a helper but this is ur journey and urs alone

Answer 6

I know but can you tell me what effect the drug will have on your body temperature, efficiency of energy utilization, and health? @raiders88

Answer 7

tht i can do

Answer 8

thanks @raiders88 yeah i didnt want you to do it for me, just give me some real examples, that will help me solve this

Answer 9

hmmm

Answer 10

yeah im not sure cause if i make something up and tell u.................it would be bad for you

Answer 11

so to be honest i tryed and no i dont know

Answer 12

im sorry tox

Answer 13

Increase in permeability of the electron transport system will result in increased metabolism, as the rate of transfer of ions controls the rate at which mitochondria can absorb&process nutrition. Think of it as accelerator of metabolism (which is mostly a good thing) But that would mean you would lose weight if you don't eat enough. Your body temperature will likely increase depending on the condition, but mostly higher metabolism means greater temperature shift in reaction to aerobic movements.

Answer 14

I believe that the hydrogen ions that are produced would create a concentration gradient that power the ATP synthase, that's where you get most of your ATP from the electron transport chain. If you reduce the H+, I'm assuming that you're not tampering with glycolysis etc. but.. that step is critical because fewer H+ ions would mean less ATP produced.

Answer 15

what's fundamental here is how crucial H+ ions are to making this process work



Based off of what @robert136 said, you can imagine if the process is sped up, higher metabolism, would coincide with higher body temperature and thus a greater need for energy. I'm using an educated guess here, but if one increases so does the other. Perhaps maybe the body can't go under such strain and maybe other processes need to be used to generate additional ATP.