MCAT Tutorial: Urinary System

\({\bf{Overview:}}\) - primary function is excretion/waste removal & maintaining homeostasis - kidneys are the principal organ of the urinary system > attached to the bladder via tubes (ureters) - bladder is connected to the urethra which excretes urine outside the body - controlled by sphincters in urethra \({\bf{Structure~of~the~Kidney:}}\) |dw:1530334966408:dw| - two regions: cortex on the outside, medulla on the inside > medulla is further composed of renal pyramids. medulla functions in ultrafiltration & osmoregulation > pyramids are made of nephrons, the basic filtering unit
\({\bf{Nephron:}}\) > renal corpuscle: the filtering unit - contains glomerulus (capillary network, high pressure) - Bowman's capsule: intakes glomerular filtrate from blood and outputs into the renal tubule > renal tubule: contains the convuluted tubules and the loop of Henle |dw:1530335367411:dw|
The Renal Tubule |dw:1530335523060:dw| > proximal tubule: site of resorption for water and glomerular filtrate - glucose, amino acids, ionis, water - passive/facilitated diffusion via sodium conc. gradient - pH regulated through hydrogen/bicarbonate buffer system > loop of Henle: contains descending limb and ascending limb - descending: permeable to water - ascending: permeable to sodium. sodium actively pumpted out, making the interstitial fliuid to be more hypertonic - movement of fluid powered by conc. gradient > distal tubule: site of active transport for water - controlled by aldosterone (which increases sodium reabsorption and potassium secretion)
\({\bf{Other~Functions~of~the~Urinary~System:}}\) Urine Collection: - the tubules empty out into a duct - controlled by ADH (antidiuretic hormone) which makes the duct more permeable to water, increasing conc. of urine. - urine travels from kidney to ureter to bladder. has internal and eternal sphincter to control movement out of the body. Blood Pressure Regulation: - kidneys contain juxtaglomerular apparatus which detects changes in BP - produces renin under low pressure conditions --> angiotensin I --> converted to angiotensin II --> increases blood pressure and aldosterone release
Anyway, that's the end of my tutorial, I hope it was a helpful resource. Source material is the 2nd Edition Barron's Prep book for the new MCAT
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