1. What are Schizophrenic and Psychotic Disorders? What causes this disorder? How do we treat it? 2. What are neurocognitive disorders? What causes them? What types of treatment are available?
@Ferredoxin4
1. Schizophrenia Spectrum
-Schizophrenia is characterized of disordered thinking, hallucinations, and the inability to distinguish between fantasy and reality. -Psychotic disorders come under the schizophrenia spectrum, and is strictly the inability to distinguish between reality and fantasy. Types of schizophrenia: 1. Paranoid - delusions that everyone is out to cause harm, delusions of persecution and grandeur. 2. Disorganized - irrational cognition and disturbing behavior. 3. Catatonic - Violent neuromuscular activity 4. Undifferentiated - has schizophrenia but does not meet diagnostic criterias of one type. 5. Residual - illogical thinking, eccentric behavior, but *has a touch with reality* Causes? 1. Biological - High dopamine levels 2. Genetic influence 3. Diasthesis/Stress-Vulnerability Model 4. Immunostimulation Signs? 1. Prenatal Maternal Viruses 2. Low attention 3. Low birth weight 4. Schizophrenia in identical twins= 50% chance of inheritance 5. Social withdrawal Treatments? 1. Medication - Antipsychotics. Specifically Clozapine, Chlorpromazine. Basically any medication that is a partial dopamine agonist. They block reuptake channels in the synaptic cleft, meaning less dopamine neurotransmission. I don't know any other treatments, you'll have to look that up. I was only taught of Partial dopamine agonists. I'll be back and answer no. 2
2. Neurocognitive/Neurodevelopmental disorders 1. ADHD - Predominantly hyperactive and impulsive, inattentive, or both. 2. Autism Spectrum Disorder - Flat effect, communicative impairment in verbal and nonverbal, limited interests 3. Asperger's syndrome - (This is a type of autism), but has a different neurological basis. More deep neurocognitive disorders - Neurodegeneration Neurodegenerative and Dementia* disorders: 1. Alzheimers - Low levels of acetylcholine 2. Lewy Body Disease - Abnormal levels of alpha-synuclein 3. Complications from TBI 4. Parkinson's - Low Dopamine 5. Prion - Incorrect protein confirmation in neuropeptides and prion proteins. 6. Unclassified neurodegenerative diseases* 7. Huntington's Chorea - Breakdown of neurons 8. MS - Demyelination, it is Auto-immune disorder 9. ALD - Another demyelination, different causing factors. *There are a trillion more, many of which are not classified yet. For example, ALD is only a few years old. *It is commonly believed that dementia is a disorder, when in fact it isn't. Dementia is the outcome of all neurodegenerative disorders, from TBI to Parkinson's. Alzheimer's is the most common form of Dementia/Neurodegeneration.
Causes: -Neurodegeneration -TBI -Genetic predisposition (ie Huntington's) Treatments: -TBH unfortunately people with neurodegenerative diseases are pretty much on their path of going downhill. There is no cure. In fact, some of these diseases weren't even in our textbooks a decade ago. -The only thing one can do as a sufferer is controlling the neurodegeneration. If it is a demyelinated disorder, then the person should have a rich Omega fatty acid-based diet to provide more nutrients for the build-up of myelin. -There's always a medication for anything, but usually, the main treatment is occupational therapy, psychological therapy, and just exercising.
Having neurodevelopmental and neurocognitive diseases shouldn't stop someone from hoping. For example, Stephen Hawking had both ALS and in return also Asperger's syndrome. However, he's a renowned scientist. Unfortunately though, people with diseases like Huntington's know that they're going to die after age 40 and have a terrifying Chorea, followed by death.
Interesting topic. I've heard that Cannabis is becoming useful as a treatment and people have been able to alleviate their neurodegenerative diseases to an extent of almost nullifying the condition.
I forgot to mention Tourette's syndrome, which would go right under Asperger's. This is excessive urges to engage in repetitive behaviors. People with Tourette's have a motor tics, commonly lip smacking and tapping
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