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Biology 9 Online
rEsTiNpEaCe:

https://gyazo.com/cc210801a8b4d7d18910e8c1e2d302d6 https://gyazo.com/3f81f3a63e32211964c5dda136decbfb

justjm:

You're trying to determine the mode of inheritance for B. It can be quite tricky and confusing in doing so, but here is a general rule that can help you out: Follow the steps to determine mode of inheritance - 1. Is the trait dominant or recessive? Traits that are more present in the population are more likely to be dominant. 2. Is there a large deviation between males and females impacted? If so, it is sex-linked and go to step 3. If not, it is autosomal and your job is finished. 3. For sex-linked only: Are all males that have the same y-chromosome impacted? If so, it is Y-linked. Otherwise, it is x-linked. In your example, they are just giving a data table out of a population. Usually, pedigrees are easier to analyze, but data is also just as fine (: It is best to make a chart or diagram to help out and employ what you know about probability. Male - 157 count P(Purple eyes) = 50 P(Tan body) = 158 P(Purple eyes AND tan body) = 57 Female - 316 count P(purple eyes) = 102 Calculate the relative frequency for each. Also, calculate the probability for all the other traits using probability rules. This way, it will be easier for you to identify the mode of inheritance given the guidelines earlier.

justjm:

To start you off, the overall proportion of purple eyes from both male or female are close to 1/3, so it is definitely autosomal.

rEsTiNpEaCe:

So, Wild type females are dominant over wild type males Purple Eyes Females are dominant over Purple Eye males

rEsTiNpEaCe:

How do you know it's close to 1/3? I'm not sure how you got that

justjm:

By chance do you have the full list of subjects, or is that all that's given? If wild type is trait in itself that is being studied then we probably can't use the method I put up there earlier

justjm:

I was thinking that they were making the overall sample population

rEsTiNpEaCe:

Should I show you a copy of the full assignment?

justjm:

Sure

rEsTiNpEaCe:

Do you got an email, it'll be easier to send you the pdf there, if you feel comfortable. otherwise, I can just take bits and bits of screenshots for you

justjm:

hm yeah you'll probably need to send it here or if it is a file just attach it on

rEsTiNpEaCe:

Ah, I forgot you can attach files lol. I've attached it below

justjm:

Yeah so unless I'm wrong, what it seems is that the breeding occurred amongst wild types, so you can use the probability frequency method and calculate for all of them. I determined that the purple trait is most likely autosomal by comparing the frequency of purple eyes in the sample of wild type males (50/157) and wild type females (102/316). They are almost the same, so it's not sex-linked.

justjm:

Now I don't know that much about the nomenclature and how to use table B1, so sorry about that.

rEsTiNpEaCe:

Ah, I see. So if the ratios are similar that means it's autosomal

rEsTiNpEaCe:

B1 is for Part B, I don't need help with that part so no worries (:

justjm:

Yeah, and from what it seems you'll need to also do a Chi-square test for independence just to see the degree of association

rEsTiNpEaCe:

Yeah, I have to do some chi-square test I think for the hypothesis and all

rEsTiNpEaCe:

When it says "Attach your data set to your report so that we know which cross you were handling" So, basically I just make a cross? For example, Purple Eye Female x Purple Eye male? or am I in the wrong direction

payload:

idk but I think it just means the type from the table b/c it says "Data set A summarizes F2 numbers from a cross between two"

rEsTiNpEaCe:

Ah, so we have to check if each trait is dominant/recessive and autosomal or X-linked?

payload:

for part b? yeah. I think that's at least what justjm is talking about.

rEsTiNpEaCe:

No, for part a

payload:

For part a your just pasting your data lol

rEsTiNpEaCe:

So I make up my own data typa thing? Since I'm doing my own hypothesis. So basically the same scenario but my own genotype and number for each?

payload:

Well I'm not sure if your making it up or you found it in your lab experiment

payload:

R you asking for help on part a or b?

rEsTiNpEaCe:

So, should I use the same one but just make the genotypes? Part A

payload:

I'm not sure it depends on ur teacher ig

justjm:

oh if you were asking for part A then I'm not sure if what I said would help out haha, I was thinking it was for part B. For part A I guess you're just posting the data and I do not think you are doing a cross

rEsTiNpEaCe:

lol yeahh. I'm basically asking for Part A question a and b

justjm:

Yeah well for part A I'm not sure what you're supposed to do, is it just posting the same table? For part B I think it has to do with the proportion of members with the trait and figuring out the mode of inheritance. I don't know about the nomenclature part though.

rEsTiNpEaCe:

Yeah, for part B there are some tutorials I have. I think I know how to do that one

rEsTiNpEaCe:

Yeah, I think so.

rEsTiNpEaCe:

Phenotype: Wild-type Female Number: 316 So my question would be is how do I come up with a genotype for this?

justjm:

Wouldn't that just be XY, unless there are wild-type and mutant-type of traits in question as well

rEsTiNpEaCe:

There are wild type, not mutant type. I found this though: https://gyazo.com/943e4a53bec7ce4efe0208039e716a54

justjm:

Ah okay. Like I said I can't help that much with the nomenclature.

rEsTiNpEaCe:

Okay, thanks for trying anyways (:

justjm:

np (:

rEsTiNpEaCe:

@Vocaloid

justus:

Here you go

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